Greg Brockman
Guest on No Priors: Artificial Intelligence | Technology | Startups. 147 claims across 1 episode, Oct 2026.
Positions over time
Every pair of statements that was compared. Only a verified change counts as a change of mind; rewording, added nuance and different questions do not.
No two statements by this speaker have been compared yet.
Predictions, in their words
As stated, each with its moment. A date appears only where the speaker gave one.
“I think that people have not yet really internalized how much the... the physics around cyber security are going to change, I think there's an opportunity to end up with a much more secure world.”
Expects: The underlying dynamics of cybersecurity will change substantially, creating an opportunity for a much more secure world; the speaker believes people have not yet grasped the extent of this change. · no date given · not yet resolved
“It can massively increase the parallelism. I think it can decrease so many of these steps in terms of their duration.”
Expects: AI can substantially increase parallelism and shorten the duration of many drug-discovery steps. · no date given · not yet resolved · In a shared prediction of 16 →
“Maybe you should have regulation that says you only are allowed to have self-driving cars in certain areas, like there are a lot of potential sort of changes to the way that you think about.”
Expects: Regulation could limit self-driving cars to designated areas. · no date given · not yet resolved
“There is some, I think these things are going to converge, no question.”
Expects: Workplace assistance and consumer assistance are likely to converge. · no date given · not yet resolved
“and so cyber spend, security spend should actually vastly outstrip software spend.”
Expects: Cybersecurity spending should greatly exceed software spending. · no date given · not yet resolved
“And I think that we now have the ability to massively accelerate scientific discovery. And there's always been this question of.”
Expects: The speaker believes AI now gives people the ability to accelerate scientific discovery substantially. · no date given · not yet resolved · In a shared prediction of 16 →
“It's really about what are the insights that are derived? And the thing that I think we will see, but I think there's promising signs of life on, is that there's beautiful insights within the work that these AIs have done.”
Expects: The speaker expects AI-generated mathematical work to contain beautiful insights, with promising signs suggesting this may be the case. · no date given · not yet resolved
“And so the fact we're seeing such incredible results with neural nets and natural language, you're just like, from first principles, you should be able to really be able to crack the language of biology.”
Expects: Neural networks should be able to understand biological systems, as suggested by their strong results in natural language, according to Greg Brockman. · no date given · not yet resolved
“But I think we will see like 80% of what is possible come to fruition very quickly.”
Expects: The speaker predicts that 80% of what is possible will be realized very quickly. · no date given · not yet resolved
“And so I think that we're going to see just like the distinctions have held for so long, I think they're going to change.”
Expects: The longstanding distinctions between consumer and enterprise are expected to change. · no date given · not yet resolved
All 33 predictions
“So first of all, I think that the best UI is no UI. And I think in AI, that is where we're going.”
Expects: AI interfaces will probably move toward a best-case experience with no conventional user interface, according to Brockman. · no date given · not yet resolved
“And I think that what we're going to see now is a moment where A lot of that debt, a lot of that tech debt is going to come to the surface. It's time for us to pay it down.”
Expects: The speaker expects accumulated internet technology debt to become more apparent and believes it is time to address it. · no date given · not yet resolved
“And so I think we can have sort of fundamentally more secure systems through the use and applications of these AI models in the right way.”
Expects: Using AI models appropriately can make systems fundamentally more secure. · no date given · not yet resolved
“we think that there is transformative potential for the good.”
Expects: OpenAI believes its models could have transformative positive effects in cybersecurity. · no date given · not yet resolved
“where software in some ways is becoming like a barrier to entry, it's becoming so cheap, you don't just want software, You want software that is reliable, that is secure, that you can believe in,”
Expects: As software becomes very cheap, people will want software that is reliable, secure, and trustworthy, rather than merely software itself. · no date given · not yet resolved
“you know sort of the just the machine just sort of gives you an answer right it's really what can a human equipped with these tools achieve that was unthinkable before and i think it's almost like the leverage of humans to do whatever you want to do it's going way way up right it's now that you can if you have a math problem you want to go solve you can solve it but what about taking that same capability applying it to biology what about if you're a small business owner and you”
Expects: AI tools greatly increase human leverage, enabling people to achieve things that were previously unthinkable. · no date given · not yet resolved
“want to be able to operate your business well like that level of intelligence that's tuned for that domain it's just going to mean that almost this sort of unthinkable results that are aligned with your goals with your desires is now going to be within the reach of everyone and that to me is so exciting”
Expects: The speaker expects domain-specific AI intelligence to help people, including small-business owners, achieve results aligned with their goals and desires, making such capabilities broadly accessible. · no date given · not yet resolved
“important points and one of maybe the underappreciated benefits that I expect from and hope for and we're starting to see from this technology is helping people know more understand more understand each other better understand the world better and I think that there are technical mechanisms that can underlie the”
Expects: Greg Brockman expects and hopes that AI technology will increasingly help people gain knowledge, understand one another, and understand the world; he says early signs of this benefit are appearing. · no date given · not yet resolved
“capable in a certain dimension and if you understand the like why it got capable in that dimension then all other fields of human endeavor that have similar properties you should also expect similar results and so in my mind like why is mathematics something that we've managed to really transform in the way that we have had such incredible results and that part of it is that our AI is now at a certain level of capability and raw intelligence”
Expects: Greg Brockman argues that once AI capability in one dimension is understood, similar results should be expected in other fields of human endeavor that share the relevant properties. · no date given · not yet resolved
“sort of case for clinical trial and all these things and it's just like you can write those things with an AI much more easily and so I think that we're going to have to look at every step of the drug discovery process and there are going to be places where the fundamental data just does not exist and so then innovations on wet labs innovation on how you actually do simulations all of this will become incredibly important but so I think that”
Expects: The drug-discovery process will need to be examined at every step, including steps where the necessary underlying data does not exist. · no date given · not yet resolved
“sort of case for clinical trial and all these things and it's just like you can write those things with an AI much more easily and so I think that we're going to have to look at every step of the drug discovery process and there are going to be places where the fundamental data just does not exist and so then innovations on wet labs innovation on how you actually do simulations all of this will become incredibly important but so I think that”
Expects: Wet-lab innovation and improved simulation methods will become extremely important for drug discovery in areas where fundamental data is missing. · no date given · not yet resolved
“sort of case for clinical trial and all these things and it's just like you can write those things with an AI much more easily and so I think that we're going to have to look at every step of the drug discovery process and there are going to be places where the fundamental data just does not exist and so then innovations on wet labs innovation on how you actually do simulations all of this will become incredibly important but so I think that”
Expects: Greg Brockman predicts that AI will make writing clinical-trial case materials and related documents much easier. · no date given · not yet resolved
“We will see these breakthroughs coming,”
Expects: Breakthroughs in applying AI to biology will occur. · no date given · not yet resolved
“super is relevant to your conditions then you'll be able to cure the person and there's plenty of precedent for it and it can massively scale up those kinds of operations i think that impact in the short run is actually very possible but material science another example and i think there's a long tail of other domains where we should just see real changes in in kind of what is possible for humanity to accomplish”
Expects: AI will greatly scale operations for finding treatments relevant to individual conditions; the speaker considers this very possible in the short run. · no date given · not yet resolved
“super is relevant to your conditions then you'll be able to cure the person and there's plenty of precedent for it and it can massively scale up those kinds of operations i think that impact in the short run is actually very possible but material science another example and i think there's a long tail of other domains where we should just see real changes in in kind of what is possible for humanity to accomplish”
Expects: AI is expected to produce substantial changes in what humanity can accomplish in materials science and many other domains. · no date given · not yet resolved
“to all of our free users was an incredible endeavor like a real huge engineering effort and it's just very easy to implement the same functionality at much higher cost for a very small number of people and so I think that what we're seeing in in the personal assistant workspace is that there is there are going to be these different market segments where different amounts of compute are going to be expended fundamentally and so sometimes when there's different level of compute it then means the product”
Expects: Personal-assistant products will use different amounts of compute across market segments. · no date given · not yet resolved
“by these so we're not sort of you know sort of competing on two fronts it's really competing on one front and i think that this is also the general direction of travel of ai is to blur the distinction between what is consumer what is enterprise we're going to have this renaissance of entrepreneurs like we're already seeing it i mean i imagine you're seeing this very concretely um”
Expects: The general direction of AI is toward blurring the distinction between consumer and enterprise products. · no date given · not yet resolved
“by these so we're not sort of you know sort of competing on two fronts it's really competing on one front and i think that this is also the general direction of travel of ai is to blur the distinction between what is consumer what is enterprise we're going to have this renaissance of entrepreneurs like we're already seeing it i mean i imagine you're seeing this very concretely um”
Expects: AI is expected to enable a renaissance of entrepreneurship; Brockman says this renaissance is already underway. · no date given · not yet resolved
“studying and trying to find different vulnerabilities out there and then thinking about how do we help the world respond how do we coordinate incident response how do we work with government how do we work with the community in order to land these as well as possible and to help people navigate through but I think that people have not yet really internalized how much the physics around cyber security are going to change I think we will end up I think there's an opportunity to end up with a much more secure world”
Expects: The speaker believes the current changes create an opportunity for the world to become much more secure. · no date given · not yet resolved
“again over time and we found a number of issues we fixed it and at some point we saturated the issues that this model was capable of finding and that's a very good story right it's like i think that the thing to realize is that we're gonna have a next model we're gonna have to repeat that process and that that will continue but at some point again i think if you think about well the code that's being written”
Expects: OpenAI will need to repeat its security-review process as new models become available. · no date given · not yet resolved
“both the fundamentals that they've gotten right which is kind of one-time investment but also the level of cyber capability they've used to defend themselves and as we shift to that world I think that we can be in a world where defenders are able to outstrip attackers but it is going to take a lot of of change right it's going to take a sort of change in terms of how we think about every organization operating and how we collectively think about critical infrastructure and resourcing them those that have sort of not had those resources to date.”
Expects: Defenders may be able to outstrip attackers, but doing so will require major changes to organizational practices and collective support and resourcing for critical infrastructure. · no date given · not yet resolved
“exactly it's becoming so cheap and so of course making sure you don't want software right you want software that is reliable that is secure that you can believe in and so to me the resilience of that software is the sort of that's exactly that's going to become even more important so I think if you have this moment we have this opportunity to you know to your point of the XKCD with the little block at the bottom of some open source maintainer like like that never made any sense Mm and”
Expects: The value of software that is reliable, secure, and trustworthy will increase as software becomes increasingly cheap. · no date given · not yet resolved
“like human judgment human values and maybe you should think of how humans will operate in the in certain fields in certain dimensions in the future whatever it is is become more like CEOs or like board members but it's important that we have that level of agency and that I think that”
Expects: In some future domains, humans may act more like CEOs or board members while retaining agency through human judgment and values. · no date given · not yet resolved
Appearances
Claims per episode
- 15 Oct 2026The Changing Physics of Cybersecurity and Drug Development with OpenAI President Greg BrockmanNo Priors: Artificial Intelligence | Technology | Startups · guest