The speaker says agents left to modify prompts autonomously may turn each small fix into the entire prompt and fail to generalize that fix into a reusable prompt.

“Um, I've noticed that, uh, that agents will, will make really nasty prompt changes if you leave them, leave them to it. Um-”

“... every little fix becomes the whole prompt.”

“Uh, and they're, they're unable to stay meta and kind of generalize, uh, the fix into, into a prompt that generalizes.”