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Machine Learning Street Talk (MLST)

How Replication Could Teach Machines What Good Science Looks Like — Edward Hughes

Can a machine learn the judgement that separates a plausible-looking result from a faithful experiment? Edward Hughes, Chief Scientist and co-founder of Inherent, joins Tim Scarfe to argue that creativity is not optimisation, and that the missing capability in AI is choosing which questions are worth asking.

Full show notes

SPONSOR:

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Edward makes the case that Move 37 was innovative rather than creative, and that the field, not the individual, decides what counts as a discovery. That reframing runs through Csikszentmihalyi, Deutsch and exaptation into open-endedness, where deceptive goals and imperfect world models turn out to be the point rather than the problem. The second half turns to the paper: Replica, a task space built by redacting figures from real papers, and Faraday, a 27-billion-parameter model trained to steer a frontier coding agent that then beats the frontier on held-out replications.

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TIMESTAMPS:

00:00:00 Cold open: Move 37, Faraday and collective intelligence

00:01:08 Sponsor: CyberFund

00:01:46 Inherent's $50M raise and the road from string theory

00:09:14 Three timescales of learning: weights, context, culture

00:13:47 Move 37 was innovative, not creative: the field decides

00:20:39 Creativity as satisficing: the urinal and evolution

00:25:06 Exaptation and the Tristan chord: creativity in context

00:30:56 Coherence for whom? Deutsch's hard-to-vary explanations

00:35:53 Why copying is creative: Deutsch and the constraint engineer

00:42:27 Societies of agents and the strong Moravec paradox

00:45:51 Evaluate in hindsight: from Lean proofs to climate change

00:51:56 Picbreeder, local goals and why discovery needs deception

00:57:21 Spaghetti proofs, translation layers and superhuman Go

01:00:37 Does nature compress? Naturalness and real patterns

01:07:36 Why replicate? Replica's redacted figures and Faraday

01:12:31 Faraday beats Codex, Claude and GLM 5.2 on held-out tasks

01:15:31 Replication to innovation: how the Transformer happened

01:18:26 Deep replication: what Faraday learns from Voyager and GNoME

01:23:37 Can the AI scientist cheat? Goodharting the judge

01:29:09 Inside Replica: scale-down, 8xB300 runs, per-task rubrics

01:34:11 The RL crisis: getting GRPO to work with per-turn credit

01:39:43 Weights vs harnesses: AlphaEvolve, DGM and EvoTune

01:45:45 The recursive company: agents cross a phase transition

01:50:35 Collective intelligence and the electric dynamo

01:55:46 What replaces OKRs? Incumbents and the burden of knowledge

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REFERENCES:

MLST Creativity Article:

https://archive.mlst.ai/read/why-creativity-cannot-be-interpolated

organization:

[00:01:47] Inherent

https://inherentlabs.ai/

other:

[00:20:51] Marcel Duchamp, Fountain

https://www.tate.org.uk/art/artworks/duchamp-fountain-t07573

[00:05:19] Human-Timescale Adaptation in an Open-Ended Task Space (Adaptive Agent)

https://arxiv.org/abs/2301.07608

[00:06:05] The AI Scientist

https://arxiv.org/abs/2408.06292

[00:12:13] Training AI Scientists to Replicate Research (Replica and Faraday)

https://arxiv.org/abs/2608.13331

[01:44:46] Evolutionary Principles in Self-Referential Learning

https://people.idsia.ch/~juergen/diploma.html

[01:59:33] Are Ideas Getting Harder to Find?

https://www.nber.org/papers/w23782

book:

[00:16:04] Creativity: Flow

https://search.worldcat.org/title/254487436

[00:26:22] Why Greatness Cannot Be Planned

https://link.springer.com/book/10.1007/978-3-319-15524-1

[00:33:03] The Beginning of Infinity

https://www.penguinrandomhouse.com/books/293575/the-beginning-of-infinity-by-david-deutsch/

[01:55:47] Laws of Knowledge

https://www.penguin.co.nz/books/the-infinite-alphabet-9780241655672

(Full list refs on YT/rescript)

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RESCRIPT:

https://app.rescript.info/session/670296ba913761d0?share=6281911cac9bdbff637f10819d4d1e5c

11 Sept 2026 · 2:01:53 · original

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