In research pursuing a virtual cell, researchers may not have handled baselines carefully enough, and subtleties such as holdout design were not always fully accounted for.

“It sounds such an, like such an obvious learning, right? Do your baselines properly, but in a field that is rushing towards the gold pot of the virtual cell, people sometimes maybe were not as careful with the baselines and there's a whole bunch of subtleties with respect to holdout and so on that, you know, wasn't always fully observed and why some of these things happen.”