DFT cannot easily simulate some properties, including superconducting temperature, and even 100 million DFT trials would be insufficient, requiring heuristics and experiments.

“Other issues, of course, like some properties like superconducting temperature cannot be easily simulated by D_F_T_ Again, like even if you do hundred million trials with D_F_T_ it won't be enough. So we have to rely on heuristics, experiments, etcetera.”