Ian Quigley describes structure-activity relationship work as improving molecules and assessing other drug-like properties, including metabolism.

“And so the flagship problem that we spent a lot of time over the past couple months on is a structure activity relationship problem. And the idea there is like, okay, I've got some molecules, and I know that they bind, maybe they bind to this protein that I want them to.”

“How do I change them to make them better? This is a very common task for medicinal chemists to do. And SAR, as it's sort of abbreviated to, also includes other stuff like certain drug-like properties, you know, does it get metabolized, all these things.”