At the time of speaking, the speaker estimated that the largest Factorio factory generated about 19 million resources per second.

“go beyond just launching a factory and you know see some of the huge factories that real players have managed to make i think the biggest one at the moment is generating something like 19 million resources a second so we have factories that you know stem from you know making maybe one resource every couple of seconds all the way to 18 20 million a second”